Friedel-Crafts acylation
Loy, Rebecca
A Friedel-Crafts acylation of anisole with maleic anhydride promoted by aluminum chloride. The reaction goes at room temperature in 30 minutes and the product can be purified via recrystallization. The final product can be analyzed by NMR and LC/MS. Students have to determine from their NMR, what is the substitution of the benzene product, ortho or para.
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